SPINA

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SPINA

http://spina.sf.net
Calculator for structure parameters of endocrine feedback loops

SPINA is free software that facilitates calculation of constant structure parameters of endocrine feedback control systems. A first successful implementation applies to evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).

This method is increasingly used in experimental research. SPINA Thyr has been evaluated in clinical trials covering more than 10,000 subjects with various disorders of thyroid homeostais. Additional applications targeting other endocrine feedback loops are currently being developed or prepared, respectively.

SPINA Thyr is a free application that calculates GT and GD. Source code is provided for Lazarus and Free Pascal. The program is compatible with most desktop Linux distributions, Mac OS X and Windows.

Related Projects




Licensing

LicenseVerified byVerified onNotes
License:BSD 2ClauseJwdietr Cmhobbs31 January 2015



Leaders and contributors

Contact(s)Role
Johannes W. Dietrich Initiator and Main Developer
Roland Gärtner Scientific Advise
C. Renate Pickardt Scientific Advise
Phil Hess Technical Advise
Ulla Mitzdorf Scientific Advise
Matthias Holzer Technical Advise
Rudolf Hörmann Scientific Advise
Martin Adler Technical Advise
John E. Midgley Scientific Advise
Martin R. Fischer Scientific Advise


Resources and communication

AudienceResource typeURI
Homepagehttp://spina.sourceforge.net
Downloadhttp://sourceforge.net/projects/spina/files
Forumhttp://sourceforge.net/p/spina/discussion
VCS Repository Webviewhttp://sourceforge.net/p/spina/code
Changeloghttp://sourceforge.net/p/spina/wiki/Version%20history/


Software prerequisites

This entry (in part or in whole) was last reviewed on 13 May 2016.



Entry












"Initiator and Main Developer" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Technical Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Technical Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Technical Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.


















Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.3 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the page “GNU Free Documentation License”.

The copyright and license notices on this page only apply to the text on this page. Any software or copyright-licenses or other similar notices described in this text has its own copyright notice and license, which can usually be found in the distribution or license text itself.