SPINA

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SPINA

http://spina.sf.net
Calculator for structure parameters of endocrine feedback loops

SPINA is free software that facilitates the calculation of constant structure parameters of endocrine feedback control systems. A first successful implementation applies to the evaluation of thyroid function. It allows for calculating the thyroid's maximum secretory capacity (GT or SPINA-GT) and the sum activity of peripheral 5'-deiodinases (GD or SPINA-GD) from levels of TSH, (F)T4 and (F)T3 that have been determined once only (SPINA Thyr).

This method is increasingly used in experimental research. SPINA Thyr has been evaluated in clinical trials covering more than 10,000 subjects with various disorders of thyroid homeostasis. Additional applications targeting other endocrine feedback loops are currently being developed or prepared, respectively.

SPINA Thyr is a free application that calculates GT and GD. Source code is provided for Lazarus and Free Pascal. The program is compatible with most desktop Linux distributions, Mac OS X and Windows.





Licensing

License

Verified by

Verified on

Notes

Verified by

Jwdietr Cmhobbs

Verified on

25 January 2020




Leaders and contributors

Contact(s)Role
Roland Gärtner Scientific Advise
Johannes W. Dietrich Initiator and Main Developer
Martin R. Fischer Scientific Advise
Martin Adler Technical Advise
Rudolf Hörmann Scientific Advise
Matthias Holzer Technical Advise
Ulla Mitzdorf Scientific Advise
C. Renate Pickardt Scientific Advise
Phil Hess Technical Advise
John E. Midgley Scientific Advise


Resources and communication

AudienceResource typeURI
R (Ref)https://cran.r-project.org/web/packages/SPINA
Forumhttp://sourceforge.net/p/spina/discussion
Downloadhttp://sourceforge.net/projects/spina/files
https://doi.org/10.5281/zenodo.3596049
Changeloghttp://sourceforge.net/p/spina/wiki/Version%20history/
VCS Repository Webviewhttp://sourceforge.net/p/spina/code
Homepagehttp://spina.sourceforge.net


Software prerequisites




Entry








"Initiator and Main Developer" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Scientific Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Technical Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Technical Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.



"Technical Advise" is not in the list (Maintainer, Contributor, Developer, Sponsor, Unknown) of allowed values for the "Role" property.


"R (Ref)" is not in the list (General, Help, Bug Tracking, Support, Developer) of allowed values for the "Resource audience" property.


















Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.3 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the page “GNU Free Documentation License”.

The copyright and license notices on this page only apply to the text on this page. Any software or copyright-licenses or other similar notices described in this text has its own copyright notice and license, which can usually be found in the distribution or license text itself.